- Barksdale Reading Institute
- Business Law Institute
- Clinic for Outreach and Personal Enrichment
- Croft Institute for International Studies
- Institute for the Arts
- Institute of Child Nutrition
- Institute for Data Science
- Grisham-McLean Institute for Public Service and Community Engagement
- Mississippi Hills Institute for Heritage Resource Management
- Mississippi Law Research Institute
- Mississippi Mineral Resources Institute
- National Institute for Undersea Science and Technology
- Research Institute of Pharmaceutical Sciences
- Trent Lott Leadership Institute
- William Magee Institute for Student Well Being