- Center for Air and Space Law
- Center for Archaeological Research
- Center for Biodiversity and Conservation Research
- Center for Clinical and Translational Science
- Center for Civil War Research
- Center for Diagnostics, Design, Devices, and Biomechanics
- Center for Economic Science and Economic Education
- Center for Excellence in Literacy Instruction
- Center for Excellence in Teaching and Learning
- Center for Graphene Research and Innovation
- Center for Health and Sports Performance
- Center for Innovation and Entrepreneurship
- Center for Intelligence and Security Studies
- Center for Mathematics and Science Education
- Center for Multi-messenger Astrophysics
- Center for Pharmaceutical Marketing and Management
- Center for Population Studies
- Center for Research Evaluation
- Center for Speech and Hearing Research
- Center for the Study of Southern Culture
- Center for Water and Wetland Resources
- Clinical-Disaster Research Center
- Community First Research Center for Wellbeing and Creative Achievement
- Declaration of Independence Center for the Study of American Freedom
- Graduate Center for the Study of Early Learning
- Haley Barbour Center for Manufacturing Excellence
- Haley Barbour Center for the Study of American Politics
- Indo-U.S. Joint Centre for Research in Indian Systems of Medicine
- Jackson Heart Study Vanguard Center at Oxford
- Jamie Whitten National Center for Physical Acoustics
- Magazine Innovation Center
- National Center for Computational Hydroscience and Engineering
- National Center for Natural Products Research
- National EDP Auditing Archival Center
- National Tax History Research Center
- National Sea Grant Law Center
- Overby Center for Southern Journalism and Politics
- Pii Center for Pharmaceutical Technology
- Sarah Isom Center for Women and Gender Studies
- Sino-U.S. Traditional Chinese Medicines Research Center
- University of Mississippi Geoinformatics Center
- William Magee Center